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Eighteen out of 20 patients with trisomy 21 have been delivered by elective cesarean section. Of the two patients with trisomy 21 and vaginal delivery, one had an infection at delivery and one had preterm labor with mild maternal and fetal complications. The risk of neonatal death and cerebral anomalies is higher than that associated with non-trisomic pregnancies. The presence of some trisomy 21 and trisomy 18 pregnancies in amniocentesis follow-up at our institution suggests that the presence of some trisomy 21 cells may not be associated with intrauterine growth retardation or other complications.Q:
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